Videos

The Blue Brain Project Movie

 

Reconstruction and simulation of neocortical microcircuitry

Images

   (High resolution images can be downloaded by clicking on the bold part of the legend)

• copyright information.pdf

 

 

Diverse neurons in silico: An in silico rendering of diverse neocortical neurons.

 

 

 

 

 

 

 

 

 

 

Predicted_synaptic_input: Predicted map of afferent synaptic input onto an exemplar thick-tufted layer 5 pyramidal neuron in a digital reconstruction of neocortical microcircuitry. Synaptic input is shown as projections called "spines". The different colours show inputs from diverse neocortical neuron types.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Neural slice preview: Simulation of electrical activity in a “virtual brain slice” formed from seven unitary digital reconstructions of neocortical microcircuits.

 

 

 

 

In_silico_basket_cell: An image of a layer 2/3 large basket cell in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

Retrograde_staining: In silico retrograde staining. The presynaptic neurons of a layer 2/3 nest basket cell (in red) were stained (in blue) in a digital reconstruction of neocortical microcircuitry. Only immediate neighbouring presynaptic neurons are shown.

 

 

 

 

 

 

 

Golgi_staining_diffuse: An in silico Golgi stain representation of exemplar neocortical neurons belonging to 55 morphological types.
 

 

 

 

 

 

 

 

 

 

 

 

 

In_silico_network_white: An in silico network of thick-tufted layer 5 pyramidal cells in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  

 

In_silico_network_black: An in silico network of thick-tufted layer 5 pyramidal cells in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

pbrt-cck: In silico labelling of cholecystokinin (CCK) expressing neuron types in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

pbrt-cr: In silico labelling of calretinin (CR) expressing neuron types in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

pbrt-npy: In silico labelling of neuropeptide-Y (NPY) expressing neuron types in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  

 

 

pbrt-pv: In silico labelling of parvalbumin (PV) expressing neuron types in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

pbrt-som: In silico labelling of somatostatin (SOM) expressing neuron types in a digital reconstruction of neocortical microcircuitry.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

pbrt-vip: In silico labelling of vasoactive intestinal polypeptide (VIP) expressing neuron types in a digital reconstruction of neocortical microcircuitry.